United States – March 15, 2022 —
Creative Biogene, one of the world’s leading biotechnology products and service providers, is dedicated to providing customized molecular biology reagents and professional technical services to satisfy the needs of customers in the field of basic life sciences research, biomedical development, industrial synthetic application and preclinical drug discovery. Recently, Creative Biogene announced the launch of its high-quality kits and materials to support mRNA synthesis.
Synthetic mRNA is widely used as a replacement molecule for plasmid DNA to modulate protein levels in therapeutic and research settings. Their biological functions depend on 5′ Cap structures and nucleotide modifications that ensure efficient translation and reduce immunogenicity. Classic combinations of modifications include ARCA (Cap 0), 5-methylcytidine, and pseudouridine, which are conveniently introduced by in vitro transcription via the correspondingly modified nucleotides. Synthetic mRNAs have become very popular for a wide range of potential applications in regenerative medicine, basic cell biology, disease therapy, and cell reprogramming.
Creative Biogene offers reagents to synthesize up to 10 micrograms of biologically active capped and tailed synthetic mRNA using de novo synthesized error-correcting gene fragments (mRNA templates) up to 1.8 kb in length. Alternative options include the choice of capping methods and the addition of N1-methyl-pseudouridine or pseudouridine nucleosides to mRNA and unmodified mRNA.
Kits provided by Creative Biogene are collections of reagents or equipment that can perform specific biological experiments. The components of the kit can be stored for a long time under suitable conditions, and researchers can complete specific experiments according to the kit’s protocol.
In addition, Creative Biogene offers a complete portfolio of cell assays to help you accelerate laboratory research. Membrane potential staining kit, calcium staining kit, mitochondrial membrane potential indicator kit, cell growth detection kit, ELISA detection kit, homogeneous cAMP detection kit, etc. The Dual Luciferase (Firefly-Renilla) Assay System is designed for high-throughput, rapid quantification of firefly and Renilla luciferases in a single sample in mammalian cell culture. Creative Biogene’s Dual Luciferase Assay Kit is the perfect choice for highly sensitive detection of firefly luciferase (FLuc) and Renilla luciferase (Rluc) activities.
“The comprehensive portfolio offered by Creative Biogene includes enzymes, PCR, vectors, transfection reagents, cDNA and shRNA, and technologies for transfection of stable cell lines.” said Marcia Brady, the marketing director of Creative Biogene, she also added, “Our in-house experts are continually committed to developing tools and innovative solutions for the biological research community, providing dedicated technical support to our global customers and customizing solutions to meet customer-specific needs.”
About Creative Biogene
Creative Biogene, a top-of-its-kind company that holds a leading position and is committed to accelerating the development of human science through biotechnology, offering innovative technologies, products, unique tools and services for research discoveries and product development. With more than 10 years of experience and in-house experts, Creative Biogene has become a well-recognized industry leader to support researchers worldwide.
Contact Info:
Name: Marcia Brady
Email: Send Email
Organization: Creative Biogene
Address: Shirley, NY 11967, USA
Phone: 1 631 386 8241
Website: https://www.creative-biogene.com/
Release ID: 89070483